I received my Z600 3 days ago and I am very, very satisfied.
Original config was: 2x Xeon 6C X5650, 48Gb RAM, 160GB Velociraptor + 500GB WD Black, Quadro 4000, Win 7Pro.
I removed Quadro, HDD's, optical drives and one bay cover and installed GTX 660, Kingston Fury 120 GB with my Win 10, 2 TB WD Blue and two more drives inside Orico hot swap bays- 1 TB Samsung F3 and 640 GB WD Blue. Also, whole thing was fully dissasembled and cleaned (alu sides were polished a bit to remove scrathes and dirt) since it was really dirty.
Only thing to do is purchase USB3 and USB2 cards and later upgrade GPU to either GTX 1060 or RX 480.